Case report: Meningitis secondary to Lyme disease

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On this case report, “Meningitis within the Guise of Dementia: Lyme-Induced Regular Strain Hydrocephalus,” Liu and colleagues evaluate the case of an aged affected person with dementia, discovered to have Lyme meningitis within the setting of a traditional stress hydrocephalus (NPH). [1]

An 80-year-old man was admitted to a hospital in Pennsylvania, an space endemic for Lyme disease, attributable to elevated weak point and confusion. He had “a number of days of nausea with decreased urge for food, generalized malaise, fatigue, and weak point,” in keeping with the authors.

Cerebrospinal fluid (CSF) research prompt aseptic meningitis. And a CT scan confirmed dilated ventricles. Remedy for regular stress hydrocephalus relieved his signs.

On the fourth day of hospitalization, the person examined optimistic for Lyme disease by Western blot on bands 23KD and 39KD.

“Healthcare suppliers treating sufferers with NPH ought to think about Lyme disease as a differential analysis due to the a number of reported instances of NPH secondary to Lyme disease.”

“The affected person was subsequently identified with aseptic meningitis secondary to Lyme,” the authors state.

He was handled with IV and oral doxycycline. However his dementia didn’t utterly resolve, “probably attributable to major dementia or different situation.”

“Within the case of our affected person, infectious meningitis was suspected attributable to this affected person reportedly having had fevers and leukocytosis. Moreover, Lyme disease is among the many most typical reportable infections in Pennsylvania,” the authors state.

Authors Conclude:

“Lyme disease … can current with a number of problems, together with arthritis, coronary heart rhythm defects, facial nerve palsy, impaired reminiscence, and meningitis. Therefore, Lyme disease needs to be thought-about as a part of the differential etiology of meningitis.”
 

References:
  1. Liu R, Polly M, Lennon RP, Reedy-Cooper A. Meningitis within the Guise of Dementia: Lyme-Induced Regular Strain Hydrocephalus. Clin Med Res. 2023 Dec;21(4):226-229. doi: 10.3121/cmr.2023.1829. PMID: 38296639.

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