Imaginative and prescient issues in affected person with Lyme disease and big cell arteritis

Imaginative and prescient issues in affected person with Lyme disease and big cell arteritis

Table of Contents

Acute imaginative and prescient loss presents as a standard scientific manifestation with numerous underlying causes, together with demyelinating ailments, neoplastic processes, autoimmune issues, and infectious situations, explains Wan et al.

Of their article “Through the Eyes of Uncertainty: Giant Cell Arteritis and Lyme Neuroborreliosis in a Story of Vision Loss,” Wan and colleagues describe a singular case through which an aged girl, who examined constructive for each big cell arteritis and Lyme disease, developed imaginative and prescient issues together with an abrupt lack of imaginative and prescient.¹

An acute lack of imaginative and prescient and different imaginative and prescient issues may be attributable to a wide range of medical situations together with an autoimmune dysfunction often known as big cell arteritis (GCA). It is a sort of vasculitis whereby sure arteries, significantly these close to the temples, develop into infected. It’s a comparatively widespread situation which can trigger jaw claudication (ache or fatigue whereas chewing), complications, and visible disturbances.

In the meantime, Lyme disease is certainly one of a number of infections that may trigger imaginative and prescient issues together with a sudden lack of imaginative and prescient.

“Though comparatively uncommon, Lyme disease may also result in optic neuritis, an optic nerve irritation leading to eye ache and blurry imaginative and prescient,” the authors level out.

Imaginative and prescient issues attributable to Lyme disease?

Of their case report, the authors describe an 80-year-old girl who was admitted to the emergency division with an abrupt onset of blurry imaginative and prescient of the left eye, right-sided weak point, dysarthria, jaw ache, headache, and left facial droop.

A temporal artery biopsy was carried out and confirmed the analysis of big cell arteritis. The affected person was handled with excessive dose corticosteroids which improved her unilateral imaginative and prescient loss however solely barely.

For the reason that girl lived in a Lyme endemic area, clinicians ordered testing for Lyme disease, which was constructive.

“Surprisingly, the Lyme IgG returned constructive in 5 bands on the Western blot, suggesting a analysis of Lyme neuroborreliosis,” the authors state.

The affected person was handled for Lyme disease with IV ceftriaxone, adopted by oral doxycycline.

“Upon discharge, the affected person’s imaginative and prescient within the left eye remained decreased however was enhancing and secure,” states Wan et al.

“Acute imaginative and prescient loss generally is a uncommon manifestation of Lyme disease.”

The authors counsel, “It’s much less possible that the affected person’s ocular signs have been attributable to Lyme neuroborreliosis, significantly contemplating the advance noticed after a excessive dose of steroids. Nonetheless, the chance can’t be totally dominated out…”

Authors Conclude:

“Healthcare suppliers in a Lyme endemic space should embody Lyme disease of their listing of differential diagnoses when assessing sufferers with acute imaginative and prescient loss/disturbance, as there exists a danger of it being both undiagnosed or overshadowed by different presenting sicknesses with analogous signs, corresponding to [giant cell arteritis] GCA.”


  1. Wan L, Yan A, Reese E, et al. (February 05, 2024) By the Eyes of Uncertainty: Large Cell Arteritis and Lyme Neuroborreliosis in a Story of Imaginative and prescient Loss. Cureus 16(2): e53623. doi:10.7759/cureus.53623

Source link


Leave a Reply

Your email address will not be published.