Of their article, “Uncommon Presentation of Pediatric Nervous System Lyme Illness: A Case Report,” Khurtsilava and colleagues describe a singular case involving a younger little one who developed seizures on account of Lyme disease. [1]
Nervous system Lyme disease has a large spectrum of manifestations, together with facial nerve palsy and subacute meningitis, which are sometimes noticed within the pediatric inhabitants, the authors state. However solely not often, have circumstances of seizures triggered by Lyme disease been reported.
In their case report, the authors describe a 4-year-old boy who was admitted to a clinic in Tbilisi, Georgia after exhibiting generalized tonic-clonic seizures that didn’t enhance with one dose of diazepam remedy.
Throughout the earlier 2 days, the kid developed elevated fatigue, refused to stroll, had two cases of falling and misplaced consciousness thrice.
“The morning of the presentation, the kid awakened feeling torpid, adopted by tonic-clonic seizures, and lack of consciousness.”
Clinicians recognized the kid with standing epilepticus and he was subsequently intubated and prescribed IV midazolam.
Nevertheless, EEG testing later revealed no epileptic patterns and no obvious trigger was recognized for the seizures.
The antibiotic Ceftriaxone was prescribed, together with acyclovir, which was discontinued after take a look at outcomes had been damaging for the herpes simplex virus.
May Lyme disease set off seizures within the younger little one?
“Regardless of non-classical manifestations, Lyme disease was thought-about,” the authors state. Subsequently, the kid examined optimistic for Lyme disease and commenced therapy with doxycycline.
“Upon discussing the outcomes with the mother and father, they recalled noticing a rash 4 months in the past, which resolved by itself,” the authors state.
One month after therapy, the kid exhibited temper modifications and sleep problems with evening terrors.
“The mom reported the presence of imaginary pals and anxiousness,” the authors state.
4 months after the preliminary prognosis, extreme behavioral issues continued, together with frequent tantrums, screaming, and hallucinations.
The kid obtained psychiatric care and these signs progressively resolved after six months, with solely delicate temper swings nonetheless current.
Authors Conclude:
- “We consider that this case underscores the significance of contemplating Lyme borreliosis within the differential prognosis when advanced neurological signs come up in pediatric sufferers.”
- “The attention of unusual scientific manifestations in pediatric sufferers with Lyme neuroborreliosis is essential for clinicians to efficiently diagnose and deal with the illness.”
- “The extended post-treatment behavioral issues elevate questions concerning the potential long-term results of neuroborreliosis and present the necessity for continued analysis right into a complete understanding of Lyme disease in pediatric sufferers.”
References:
- Khurtsilava I, Kanjaradze D, Tsirdava N, et al. (Could 18, 2024) Uncommon Presentation of Pediatric Nervous System Lyme Illness: A Case Report. Cureus 16(5): e60535. doi:10.7759/cureus.60535